Author

T. H. Jensen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

W. Garland· 2 shared A. A. Jeyaprakash· 1 shared A. Kettenbach· 1 shared A.-E. Foucher· 1 shared B. Lopez-Mendez· 1 shared B. McEwan· 1 shared B. Schwalb· 1 shared B. T. Chait· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

W. Garland

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Substrate recognition principles for the PP2A-B55 protein phosphatase

T. Kruse, D. Garvanska, J. K. Varga, W. Garland, B. McEwan, J. Hein, M. B. Weisser, I. B. Puy, C. Chan, P. S. Parrila, B. Lopez-Mendez, A. A. Jeyaprakash, O. Schueler-Furman, T. H. Jensen, A. Kettenbach, J. Nilsson

The paper identifies conserved mechanisms by which PP2A-B55 substrates bind B55 through α-helices and develops a competitive inhibitor to study its function.

bioRxiv · Feb 10, 2024Cell Biology

Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex

E. Dubiez, E. Pellegrini, M. Finderup Brask, W. Garland, A.-E. Foucher, K. Huard, T. H. Jensen, S. Cusack, J. Kadlec

The paper reveals how different effectors compete for binding to the CBC-ARS2 complex, influencing RNA fate through structural and biochemical analysis.

bioRxiv · Jul 25, 2023Biochemistry

Integrator is a genome-wide attenuator of non-productive transcription

S. Lykke-Andersen, K. Zumer, E. S. Molska, G. Wu, J. O. Rouviere, C. Demel, B. Schwalb, M. Schmid, P. Cramer, T. H. Jensen

The paper identifies genome-wide roles of the Integrator complex in attenuating non-productive transcription by dampening weak promoters and quality-controlling RNAPII complexes.

bioRxiv · Jul 17, 2020Cell Biology

Affinity proteomic dissection of the human nuclear cap-binding-complex interactome

Y. Dou, S. Kalmykova, M. Pashkova, M. Oghbaie, H. Jiang, K. R. Molloy, B. T. Chait, M. P. Rout, D. Fenyo, T. H. Jensen, I. Altukhov, J. LaCava

This study maps the human nuclear cap-binding complex interactome using affinity proteomics to clarify the composition and interactions of NCBP1, NCBP2, and NCBP3-related macromolecular assemblies.

bioRxiv · Apr 20, 2020Biochemistry