Author

M. Tully

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:protein structure· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

A. B. Ludi· 1 shared A. Burman· 1 shared A. Gray· 1 shared A. Kalantzi· 1 shared A. Keeble· 1 shared A. S. Asfor· 1 shared A. Zagrajek· 1 shared B. Charleston· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. B. Ludi

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Author profile →

3 papers

Recent·Most cited

Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation

P. Juyoux, I. Galdadas, D. Gobbo, J. von Velsen, M. Pelosse, M. Tully, O. Vadas, F. L. Gervasio, E. Pellegrini, M. W. Bowler

The paper determines the structure and activation mechanism of the MKK6-p38α complex using cryo-EM and MD simulations, revealing how phosphorylation and interactions drive MAPK specificity.

bioRxiv · Jul 4, 2022Biophysics

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

T. K. Tan, P. Rijal, R. Rahikainen, A. Keeble, L. Schimanski, S. Hussain, R. Harvey, J. Hayes, J. Edwards, R. McLean, V. Martini, M. Pedrera, N. Thakur, C. Conceicao, I. Dietrich, , R. Owens

This study develops a vaccine candidate using SpyCatcher technology to display the SARS-CoV-2 RBD, showing strong neutralizing antibody responses in mice and pigs.

bioRxiv · Aug 31, 2020Immunology

KAP1 is an antiparallel dimer with a natively functional asymmetry

G. Fonti, M. Marcaida, L. Bryan, S. Traeger, A. Kalantzi, P.-Y. Helleboid, D. Demurtas, M. Tully, S. Grudinin, D. Trono, B. Fierz, M. Dal Peraro

This paper shows KAP1 forms an antiparallel dimer with a native asymmetry, which affects its SUMOylation and interaction with HP1.

bioRxiv · Feb 19, 2019Biophysics