Author

E. Reuveni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:genetic perturbation / CRISPR· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

U. Ben-David· 3 shared A. S. Kadmon· 2 shared F. Vazquez· 2 shared G. De Feudis· 2 shared J. Zerbib· 2 shared K. Laue· 2 shared M. R. Ippolito· 2 shared S. Martin· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

U. Ben-David

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage

J. Zerbib, M. R. Ippolito, Y. Eliezer, G. De Feudis, E. Reuveni, A. S. Kadmon, S. Martin, S. Vigano', G. Leor, J. Berstler, K. Laue, Y. Cohen-Sharir, S. Scorzoni, F. Vazquez, U. Ben-David, S. Santaguida

This study identifies the RAF/MEK/ERK pathway as a critical dependency for aneuploid cells, showing increased pathway activity and sensitivity to its inhibition in aneuploid cancer cells.

bioRxiv · Jan 27, 2023Cancer Biology

Increased RNA and protein degradation is required for counteracting transcriptional burden and proteotoxic stress in human aneuploid cells

M. R. Ippolito, J. Zerbib, Y. Eliezer, E. Reuveni, S. Vigano', G. De Feudis, A. S. Kadmon, I. Vigorito, S. Martin, K. Laue, Y. Cohen-Sharir, S. Scorzoni, F. Vazquez, S. Santaguida, U. Ben-David

This study identifies increased RNA and protein degradation as mechanisms by which aneuploid cells counteract transcriptional burden and proteotoxic stress, revealing potential therapeutic targets.

bioRxiv · Jan 27, 2023Cancer Biology

Frequent Aneuploidy in Primary Human T Cells Following CRISPR-Cas9 cleavage

A. D. Nahmad, E. Reuveni, E. Goldschmidt, T. Tenne, M. Liberman, M. Horovitz-Fried, R. Khosravi, H. Kobo, E. Reinstein, A. Madi, U. Ben-David, A. Barzel

This study finds frequent aneuploidy and chromosomal truncations in CRISPR-Cas9-edited primary human T cells, associated with reduced proliferation and p53 activation.

bioRxiv · Aug 20, 2021Bioengineering