Author

E. Sanchez-Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Ast· 1 shared A. Boeddrich· 1 shared A. Buntru· 1 shared A. Dudziak· 1 shared A. Gilg· 1 shared A. M. Abadi· 1 shared A. Nicolo· 1 shared A. S. Wagner· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiochemistry

A. Ast

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Conformational plasticity of a BiP-GRP94 chaperone complex

J. C. Brenner, L. C. Zirden, Y. Almeida-Hernandez, F. Kaschani, M. Kaiser, E. Sanchez-Garcia, S. Poepsel, D. Hellerschmied

This study characterizes the conformational changes of the BiP-GRP94 chaperone complex and identifies the structural basis of their interaction without co-chaperones.

bioRxiv · Feb 1, 2024Biochemistry

Differentially accessible Cdc4 phospho-degrons regulate Ctf19CCAN kinetochore subunit stability in mitosis

S. Westermann, M. Böhm, K. Killinger, A. Dudziak, P. Pant, K. Jänen, S. Hohoff, K. Mechtler, M. Örd, M. Loog, E. Sanchez-Garcia

The paper shows that phosphorylation of Cdc4 phospho-degrons on Ame1CENP-U regulates its stability during mitosis by targeting it for degradation, with the Mtw1 complex protecting it from degradation.

bioRxiv · Feb 12, 2021Cell Biology

An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

m. Harmse, M. M. Habib, S. Nemska, A. Nicolo, A. Gilg, N. Preising, P. Sokkar, S. Carmignani, M. Raasholm, G. Weidinger, G. Kizilsavas, M. Wagner, L. Staendker, A. M. Abadi, H. Jumaa, , J. Muench

The paper develops an optimized CXCR4 antagonist, JM#21, which effectively prevents atopic dermatitis and airway inflammation in mouse models.

bioRxiv · Aug 28, 2020Immunology

Self-assembly of mutant huntingtin exon-1 fragments into large complex fibrillar structures involves nucleated branching

A. S. Wagner, A. Z. Politi, A. Ast, K. Bravo-Rodriguez, K. Baum, A. Buntru, N. U. Strempel, L. Brusendorf, C. Haenig, A. Boeddrich, S. Plassmann, K. Klockmeier, J. M. Ramirez-Anguita, E. Sanchez-Garcia, J. Wolf, E. E. Wanker

This study investigates the self-assembly of mutant huntingtin exon-1 fragments into complex fibrillar structures, identifying two nucleation mechanisms and their role in fibril formation.

bioRxiv · Mar 15, 2018Biochemistry