Author

H. Jumaa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:zebrafish· 1

Frequent Co-Authors

A. Nicolo· 2 shared J. Jellusova· 2 shared M. M. Taketo· 2 shared A. Gilg· 1 shared A. M. Abadi· 1 shared C. S. Setz· 1 shared C. Setz· 1 shared D. Fonseca-Arce· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

A. Nicolo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies

K. N. Cosgun, H. Jumaa, M. E. Robinson, X. Liang, G. Xiao, L. N. Chan, J. Lee, K. Kume, E. Leveille, D. Fonseca-Arce, D. Khanduja, H. L. Ng, N. Feldhahn, J. Song, W. C. Chan, , M. Mueschen

This study identifies a unique vulnerability in B-cell malignancies where GSK3β inhibitors disrupt β-catenin-Ikaros complexes, leading to MYC repression and cell death.

bioRxiv · Mar 13, 2023 · PreprintCancer Biology

Accumulation of the GSK3 target protein β-catenin is lethal for B cell precursors and malignant B cells

H. Jumaa, K. M. Kistner, C. Setz, M. M. Taketo, H. Jumaa, J. Jellusova

This study shows that β-catenin accumulation caused by GSK3 inhibition leads to reduced survival in B cell precursors and malignant B cells.

bioRxiv · Sep 17, 2021 · PreprintImmunology

Antibodies control metabolism by regulating insulin homeostasis

T. Amendt, G. Allies, A. Nicolo, O. El Ayoubi, M. Young, T. Roeszer, C. S. Setz, K. Warnatz, H. Jumaa

This study identifies anti-insulin IgM antibodies that regulate insulin homeostasis by counteracting neutralizing IgG antibodies, preventing blood glucose dysregulation.

bioRxiv · Aug 10, 2021 · PreprintImmunology

An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

m. Harmse, M. M. Habib, S. Nemska, A. Nicolo, A. Gilg, N. Preising, P. Sokkar, S. Carmignani, M. Raasholm, G. Weidinger, G. Kizilsavas, M. Wagner, L. Staendker, A. M. Abadi, H. Jumaa, , J. Muench

The paper develops an optimized CXCR4 antagonist, JM#21, which effectively prevents atopic dermatitis and airway inflammation in mouse models.

bioRxiv · Aug 28, 2020Immunology