Author

E. Shortt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

S. Lourido· 5 shared A. L. Herneisen· 2 shared T. A. Smith· 2 shared A. W. Chan· 1 shared C. G. Hackett· 1 shared D. M. Sabatini· 1 shared E. A. Boydston· 1 shared E. Andree· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersMicrobiology

S. Lourido

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

SPARK regulates AGC kinases central to the Toxoplasma gondii asexual cycle

A. L. Herneisen, M. L. Peters, T. A. Smith, E. Shortt, S. Lourido

This study shows SPARK regulates PKA and PKG stability in Toxoplasma gondii, affecting its asexual cycle transitions.

bioRxiv · Oct 30, 2023Microbiology

Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma

A. W. Chan, M. Broncel, E. Yifrach, N. R. Haseley, S. Chakladar, E. Andree, A. L. Herneisen, E. Shortt, M. Treeck, S. Lourido

This study identifies CDPK1 targets in Toxoplasma gondii, revealing a trafficking adaptor complex that regulates microneme exocytosis and host cell invasion.

bioRxiv · Jan 11, 2023 · PreprintMicrobiology

CDPK2A and CDPK1 form a signaling module upstream of Toxoplasma motility

E. Shortt, C. G. Hackett, R. V. Stadler, G. E. WARD, S. Lourido

This paper identifies CDPK2A and CDPK1 as a signaling module regulating Toxoplasma motility, showing their functional interaction and role in microneme discharge and egress.

bioRxiv · Jul 19, 2022 · PreprintMicrobiology

High-throughput functionalization of the Toxoplasma kinome uncovers a novel regulator of invasion and egress

T. A. Smith, G. S. Lopez-Perez, E. Shortt, S. Lourido

This study uses a high-throughput CRISPR system to functionally analyze the Toxoplasma kinome, identifying SPARK as a novel regulator of invasion and egress.

bioRxiv · Sep 23, 2021 · PreprintMicrobiology

A PEROXO-Tag enables rapid isolation of peroxisomes from human cells

G. J. Ray, E. A. Boydston, E. Shortt, G. A. Wyant, S. Lourido, W. W. Chen, D. M. Sabatini

This paper introduces a PEROXO-Tag and PEROXO-IP workflow for rapid and specific isolation of human peroxisomes, validated through proteomic profiling.

iScience · May 1, 2020Peer-reviewedCell Biology