Author

E. W. Scadden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. Scadden· 2 shared K. Gustafsson· 2 shared A. E. Boitano· 1 shared C. Burns· 1 shared C. P. Lin· 1 shared C. Rhee· 1 shared H. Gessessew· 1 shared J. A. Spencer· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

D. Scadden

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer

K. Gustafsson, C. Rhee, V. Frodermann, E. W. Scadden, Y. Iwamoto, R. Palchaudhuri, S. L. Hyzy, A. E. Boitano, M. Nahrendorf, D. Scadden

This study shows that anti-CD45-ADC clears tissue-resident myeloid cells, enabling efficient replacement with donor cells and reducing atherosclerotic plaque burden.

bioRxiv · Sep 5, 2023 · PreprintImmunology

Thymic mesenchymal niche cells drive T cell immune regeneration

K. Gustafsson, S. Isaev, K. A. Kooshesh, N. Baryawno, K. D. Kokkaliaris, N. Severe, T. Zhao, E. W. Scadden, J. A. Spencer, C. Burns, K. Akilan, N. Barkas, H. Gessessew, C. P. Lin, P. V. Kharchenko, D. Scadden

This study identifies a thymic mesenchymal niche cell subset that supports T cell regeneration and shows its therapeutic potential in reversing thymic atrophy.

bioRxiv · Oct 12, 2022Immunology