Author

S. Murali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Bioengineering· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:non-human primate· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

D. Hughes· 2 shared J. Rogers· 2 shared K. C. Worley· 2 shared M. Raveendran· 2 shared M. W. Hahn· 2 shared R. A. Harris· 2 shared A. Jalali· 1 shared A. Majumder· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersEvolutionary Biology

D. Hughes

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Integrating molecular and clinical variables to predict myocardial recovery

J. R. Visker, B. J. Brintz, C. P. Kyriakopoulos, Y. Hillas, I. Taleb, R. Badolia, T. S. Shankar, J. M. Amrute, J. Ling, R. Hamouche, E. Tseliou, S. Navankasattusas, O. Wever-Pinzon, G. S. Ducker, W. L. Holland, , S. G. Drakos

This study integrates clinical and transcriptomic data to predict myocardial recovery in heart failure patients after LVAD implantation, identifying 80 features with an AUC of 0.731.

bioRxiv · Apr 16, 2024 · PreprintPhysiology

Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects

S. Omo-Lamai, Y. Wang, M. N. Patel, E.-o. Essien, M. Shen, A. Majumder, C. Espy, J. Wu, B. Channer, M. P. Tobin, S. Murali, T. E. Papp, R. Maheshwari, L. Wang, L. S. Chase, , J. S. Brenner

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

bioRxiv · Apr 16, 2024 · PreprintBioengineering

Remote neuronal activity drives glioma infiltration via Sema4f

E. Huang-Hobbs, Y.-T. Cheng, Y. Ko, E. Luna-Figueroa, B. Lozzi, K. Taylor, M. McDonald, P. He, H.-C. Chen, Y. Yang, E. Maleki, Z.-F. Lee, S. Murali, M. Williamson, D. Choi, , B. Deneen

This study identifies callosal projection neurons as drivers of glioma infiltration through Sema4F-mediated activity-dependent signaling in mouse and human tumors.

bioRxiv · Mar 15, 2023 · PreprintCancer Biology

Primate phylogenomics uncovers multiple rapid radiations and ancient interspecific introgression

D. Vanderpool, B. Q. Minh, R. Lanfear, D. Hughes, S. Murali, R. A. Harris, M. Raveendran, D. M. Muzny, R. A. Gibbs, K. C. Worley, J. Rogers, M. W. Hahn

This study uses genome-wide data to resolve primate phylogenetic relationships, identifying multiple radiations and ancient introgression events.

bioRxiv · Apr 15, 2020Evolutionary Biology

Reproductive longevity predicts mutation rates in primates

G. W. C. Thomas, R. J. Wang, A. Puri, R. A. Harris, M. Raveendran, D. Hughes, S. Murali, L. Williams, H. Doddapaneni, D. Muzny, R. Gibbs, C. Abee, M. R. Galinski, K. C. Worley, J. Rogers, , M. W. Hahn

The paper shows that paternal age determines de novo mutation rates in owl monkeys and proposes a model linking reproductive longevity to mutation rates across primates.

bioRxiv · May 21, 2018Evolutionary Biology