Author

Edward C.G. Pym

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Drosophila· 2 Organism:C. elegans· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Angela H. DePaceiD· 2 shared Ben J. VincentiD· 2 shared Francheska López-RiveraiD· 2 shared Javier EstradaiD· 2 shared Meghan D. J. BragdoniD· 2 shared Zeba WunderlichiD· 2 shared Joshua M. KaplaniD· 1 shared Kelly M. BietteiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenetics

Angela H. DePaceORCID

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3 papers

Recent·Most cited

MEF-2 repression of GEM-4/Copine expression decreases muscle excitability by increasing gap junction coupling

Luna Gao, Edward C.G. Pym, Stephen Nurrish, Joshua M. Kaplan

The paper identifies gem-4/Copine as a target of MEF-2 and CRH-1/CREB that reduces gap junction coupling and increases muscle excitability in C. elegans.

bioRxiv · Sep 14, 2026 · PreprintNeuroscience

A mutation in the Drosophila melanogaster eve stripe 2 minimal enhancer is buffered by flanking sequences

Francheska López-Rivera, Olivia K. Foster, Ben J. Vincent, Edward C.G. Pym, Meghan D. J. Bragdon, Javier Estrada, Angela H. DePace, Zeba Wunderlich

The paper shows that a mutation in a minimal enhancer of Drosophila eve stripe 2 is buffered by flanking sequences in extended enhancer constructs, but not in the endogenous context.

G3 Genes Genomes Genetics · Oct 9, 2020Peer-reviewedGenetics

Caudal counter-represses Hunchback to regulate even-skipped stripe 2 expression in Drosophila embryos

Ben J. Vincent, Max Valentín Staller, Francheska López-Rivera, Meghan D. J. Bragdon, Edward C.G. Pym, Kelly M. Biette, Zeba Wunderlich, Timothy T. Harden, Javier Estrada, Angela H. DePace

The paper shows that Caudal counter-represses Hunchback to enable even-skipped stripe 2 expression in Drosophila embryos, challenging the traditional view of Hunchback as a direct activator.

PLoS Genetics · Sep 7, 2018Peer-reviewedGenetics