Author

Edward Dong

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Christian Clark KrammeiD· 2 shared Emma TysingeriD· 2 shared Garyk BrixiiD· 2 shared George McDonald ChurchiD· 2 shared Merrick Pierson SmelaiD· 2 shared Mutsumi KobayashiiD· 2 shared Patrick R.J. FortunaiD· 2 shared Pranam ChatterjeeiD· 2 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Christian Clark KrammeORCID

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2 papers

Recent·Most cited

Directed Differentiation of Human iPSCs to Functional Ovarian Granulosa-Like Cells via Transcription Factor Overexpression

Merrick Pierson Smela, Christian Clark Kramme, Patrick R.J. Fortuna, Jessica L Adams, Rui Su, Edward Dong, Mutsumi Kobayashi, Garyk Brixi, Venkata Srikar Kavirayuni, Emma Tysinger, Richie E. Kohman, Toshi Shioda, Pranam Chatterjee, George McDonald Church

This study generates functional ovarian granulosa-like cells from human iPSCs by overexpressing NR5A1 and RUNX1 or RUNX2, enabling the formation of ovary-like organoids with germ cells.

eLife · Jan 19, 2023Peer-reviewedDevelopmental Biology

Rapid Human Oogonia-like Cell Specification via Combinatorial TF-Directed Differentiation

Christian Clark Kramme, Merrick Pierson Smela, Bennett K. Wolf, Patrick R.J. Fortuna, Garyk Brixi, Kalyan Palepu, Edward Dong, Jessica Adams, Suhaas Bhat, Sabrina Koseki, Emma Tysinger, Teodora Stan, Richie E. Kohman, Songlei Liu, Mutsumi Kobayashi, , Pranam Chatterjee

This study identifies key transcription factors that drive the rapid differentiation of human induced pluripotent stem cells into oogonia-like cells using a combinatorial approach and computational tools.

bioRxiv · Jul 11, 2022 · PreprintDevelopmental Biology