Associations between fluid biomarkers and PET imaging (UCB-J) of synaptic pathology in Alzheimer's disease
Johanna Nilsson, Adam P. Mecca, Nicholas James Ashton, Elaheh Salardini, Ryan S. O’Dell, Richard E. Carson, Andréa Lessa Benedet, Kaj Blennow, Henrik Zetterberg, Christopher H. van Dyck, Ann Brinkmalm
The paper examines the relationship between SV2A PET imaging and CSF synaptic protein levels in Alzheimer's disease patients and cognitively normal individuals, finding associations between lower synaptic density and specific protein markers.
Alzheimer s & Dementia · Jul 1, 2025Peer-reviewedNeuroscience