Author

Ryan S. O’Dell

Yale UniversityORCID 0000-0001-7673-6661Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein sequence· 1

Frequent Co-Authors

Adam P. MeccaiD· 3 shared Christopher H. van DyckiD· 3 shared Richard E. CarsoniD· 3 shared Elaheh Salardini· 2 shared Andréa Lessa BenedetiD· 1 shared Ann BrinkmalmiD· 1 shared Brienne MineriD· 1 shared Em Tchorz· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersNeuroscience

Adam P. MeccaORCID

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3 papers

Recent·Most cited

NeuroscienceThe American Journal of Geriatric Psychiatry Open Science Education and PracticePeer-reviewedMay 14, 2026

Basal forebrain volume is associated with cortical amyloid burden in cognitively unimpaired older adults at varying genetic risk for Alzheimers disease

Gawon Cho, Kaitlin Kelly, Takuya Toyonaga…·Ryan S. O’Dell

This study finds that nucleus basalis of Meynert (Ch4) volume is inversely associated with cortical amyloid burden in cognitively unimpaired adults at varying genetic risk for Alzheimer's disease.

2 citationstop 4%

humanimaging

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NeuroscienceAlzheimer s & DementiaPeer-reviewedJul 1, 2025

Associations between fluid biomarkers and PET imaging (UCB-J) of synaptic pathology in Alzheimer's disease

Johanna Nilsson, Adam P. Mecca, Nicholas James Ashton…·Ann Brinkmalm

The paper examines the relationship between SV2A PET imaging and CSF synaptic protein levels in Alzheimer's disease patients and cognitively normal individuals, finding associations between lower synaptic density and specific protein markers.

6 citations

humanprotein sequence

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PathologyAlzheimer s Research & TherapyPeer-reviewedMay 6, 2025

Assessment of the relationship between synaptic density and metabotropic glutamate receptors in early Alzheimer's disease: a multi-tracer PET study

Elaheh Salardini, Ryan S. O’Dell, Em Tchorz…·Adam P. Mecca

This study uses PET imaging to show a strong positive correlation between mGluR5 and synaptic density in early AD patients and cognitively normal individuals, suggesting mGluR5 may mediate early synaptic loss in AD.

8 citationstop 5%

humanimaging

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