Author

Eleanor Lewis

Canada's Michael Smith Genome Sciences Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:database / resource· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Eric Chuah· 3 shared Erin PleasanceiD· 3 shared Janessa J. LaskiniD· 3 shared Jessica NelsoniD· 3 shared Marco A. MarraiD· 3 shared Steven J.M. JonesiD· 3 shared Andrew J. J. MungalliD· 2 shared Cameron J. GrisdaleiD· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Eric Chuah

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Author profile →

3 papers

Recent·Most cited

Long-read sequencing of an advanced cancer cohort resolves rearrangements, unravels haplotypes, and reveals methylation landscapes

Kieran O’Neill, Erin Pleasance, Jeremy Fan, Vahid Akbari, Glenn Chang, Katherine Dixon, Veronika Csizmók, Signe MacLennan, Vanessa Porter, Andrew Galbraith, Cameron J. Grisdale, Luka Culibrk, John H. Dupuis, Richard Corbett, James Hopkins, , Steven J.M. Jones

This paper presents a long-read sequencing dataset of cancer samples, showing its ability to resolve structural variants, haplotypes, and methylation patterns in precision medicine.

Cell Genomics · Oct 14, 2024Peer-reviewedGenetic & Genomic Medicine

Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities

Yuka Takemon, Erin Pleasance, Alessia Gagliardi, Christopher S. Hughes, Veronika Csizmók, Kathleen Wee, Diane L.N. Trinh, Ryan D. Huff, Andrew J. J. Mungall, Richard A. Moore, Eric Chuah, Karen Mungall, Eleanor Lewis, Jessica Nelson, Howard John Lim, , Marco A. Marra

bioRxiv · Jan 17, 2024 · PreprintBioinformatics

A Platform for Oncogenomic Reporting and Interpretation

Caralyn Reisle, Laura M. Williamson, Erin Pleasance, Anna Davies, Brayden Pellegrini, Dustin W. Bleile, Karen Mungall, Eric Chuah, Martin R. Jones, Yussanne P. Ma, Eleanor Lewis, Isaac Beckie, David Pham, Raphael Matiello Pletz, Amir Muhammadzadeh, , Steven J.M. Jones

PORI is an open-source platform for interpreting somatic variants in cancer, demonstrating that 88.2% of TCGA tumors have at least one potentially targetable alteration.

Nature Communications · Feb 9, 2022Peer-reviewedBioinformatics