Janessa J. Laskin

Parent-of-Origin-Aware Genomic Analysis to Enhance Cascade Testing in Pancreatic Cancer: A Population-Based Study

This study evaluates Parent-of-Origin-Aware genomic analysis (POAga) to improve cascade testing in pancreatic cancer families by clarifying familial risk.

Neutrophil Extracellular Trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting metastasis of pancreatic tumours

The paper identifies gene expression signatures related to neutrophil extracellular traps (NETs) in pancreatic ductal adenocarcinoma (PDAC) and shows they correlate with patient survival and metastasis, with potential therapeutic targets.

Long-read sequencing of an advanced cancer cohort resolves rearrangements, unravels haplotypes, and reveals methylation landscapes

This paper presents a long-read sequencing dataset of cancer samples, showing its ability to resolve structural variants, haplotypes, and methylation patterns in precision medicine.

Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities

A Platform for Oncogenomic Reporting and Interpretation

PORI is an open-source platform for interpreting somatic variants in cancer, demonstrating that 88.2% of TCGA tumors have at least one potentially targetable alteration.