Ellen E Quillen

Pseudo-observations of longevity improve detection of resilience-associated genes in the Radiation Late Effects Cohort of rhesus macaques.

The paper uses pseudo-observations of longevity to identify resilience-associated genes in rhesus macaques exposed to radiation and aging challenges.

Integrative Multi-Omics Analysis Reveals Molecular Signatures of Age-Related Decline in Vervet Leg Skeletal Muscle

The paper identifies a molecular signature of age-related decline in vervet monkey skeletal muscle through multi-omics analysis, highlighting miRNA and epigenetic changes associated with sarcopenia.

The Non-Human Primate Sample Size Calculator: a design tool for longitudinal research projects

The paper develops a web-based tool to estimate sample sizes for non-human primate longitudinal studies using natural healthspan data.

Developing And Internally Validating AI-Based Aging Resilience Biomarkers in Non-Human Primates

The paper develops and validates AI-based aging resilience biomarkers in non-human primates using longitudinal clinical data from baboons and rhesus macaques.

Comparative lifespan and healthspan of nonhuman primate species common to biomedical research

This study computes sex-specific survival curves for 12 nonhuman primate species to characterize aging patterns and provides insights into lifespan and healthspan differences.

Integrated Omics Analysis Reveals Sirtuin Signaling is Central to Hepatic Response to a High Fructose Diet

The paper integrates transcriptomics, proteomics, and metabolomics data from vervet monkeys to identify sirtuin signaling and PPARA network alterations in response to a high fructose diet.

Circulating miRNAs associated with bone mineral density in healthy adult baboons.

The paper identifies five miRNAs associated with bone mineral density in healthy adult baboons, suggesting their role in normal aging and potential disease mechanisms.

An evolutionary perspective of DNA methylation patterns in skeletal tissues using a nonhuman primate model of osteoarthritis

This study examines DNA methylation patterns in baboon skeletal tissues to understand their evolutionary relationship with osteoarthritis, finding conserved and divergent epigenetic features compared to humans.

Insights into the genetic architecture of the human face

This study identifies 203 genomic regions associated with facial variation using GWAS on multivariate shape phenotypes, revealing novel regions and epistatic interactions.

Intra- and Inter-Specific Investigations of Skeletal DNA Methylation and Femur Morphology in Primates

This study investigates DNA methylation in skeletal tissues of nonhuman primates to explore its association with femur morphology and species-specific traits.

Genes Affecting Vocal and Facial Anatomy Went Through Extensive Regulatory Divergence in Modern Humans

The paper identifies extensive methylation changes in genes related to facial and vocal anatomy in modern humans compared to ancient humans and chimpanzees.

Assessment of DNA methylation patterns in the bone and cartilage of a nonhuman primate model of osteoarthritis

This study assesses DNA methylation patterns in baboon bone and cartilage to identify associations with osteoarthritis and evaluate evolutionary conservation.