Nucleosome context regulates chromatin reader preference
Matthew R. Marunde, Irina K Popova, Nathan W Hall, Anup Vaidya, James R. Bone, Brandon A. Boone, Peter J. Brown, Ryan J. Ezell, Tessa M. Firestone, Harrison A. Fuchs, Elisa Gibson, Zachary B Gillespie, Susan L. Gloor, Allison R. Hickman, Sarah A Howard, , Jonathan M. Burg
The paper investigates how nucleosome context influences chromatin reader binding preferences using biochemical and genomic approaches, revealing that multivalent engagement often has regulatory effects beyond simple additivity.
Nucleic Acids Research · Oct 1, 2025Peer-reviewedBiochemistry