Author

Ernie Lee

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adelaide Herman· 1 shared Andrea Gallardo· 1 shared Andrew S. GoldsteiniD· 1 shared Angel RuiziD· 1 shared Blake R. WildeiD· 1 shared Bo LiuiD· 1 shared Braden PateiD· 1 shared Chad M. Smith· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Adelaide Herman

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Author profile →

2 papers

Recent·Most cited

Discovery of A Small Molecule non-IMiD Degrader of ZBTB7A for the Treatment of β-hemoglobinopathies

Jun Liu, Ziyang Shen, Shin‐Young Park, Yanhua Dong, Na Yu, Jing Zeng, Hannah Lee, Braden Pate, Sophia Adamia, Kim Vanuytsel, Junyan Zhang, Shang-Chuen Wu, Adelaide Herman, Shiva Moein, Wenhui Liu, , Li Chai

This paper discovers and characterizes SH6, a small molecule degrader of ZBTB7A that increases fetal hemoglobin expression in erythroid cells and shows therapeutic potential for β-hemoglobinopathies.

bioRxiv · Sep 17, 2025 · PreprintCell Biology

OGDHL regulates tumor growth, neuroendocrine marker expression, and nucleotide abundance in prostate cancer

Matthew J. Bernard, Angel Ruiz, Johnny A. Diaz, Nicholas M. Nunley, Rachel Dove, Shile Zhang, Ernie Lee, Kylie Y. Heering, Sachi Bopardikar, Andrea Gallardo, Takao Hashimoto, Raag Agrawal, Chad M. Smith, Blake R. Wilde, Nedas Matulionis, , Andrew S. Goldstein

This study identifies OGDHL as a regulator of tumor growth, neuroendocrine marker expression, and nucleotide abundance in prostate cancer, with implications for treatment resistance.

bioRxiv · May 28, 2025 · PreprintCancer Biology