ECgo: All-Optical Induction of Single Endothelial Cell Injury and Capillary Occlusion in the Brain
Jacqueline Condrau, Srinivasarao Allu, Tatiana V. Esipova, Eva Erlebach, Matthias Tasso Wyss, Chaim Glück, Luca Ravotto, Thomas Troxler, Mikhail Drobizhev, Marco Villa, Paola Ceroni, Mohamad El Amki, Sergei A. Vinogradov, Bruno Weber
The paper introduces ECgo, an optical method to induce single endothelial cell injury and capillary occlusion in the mouse brain with high spatial precision, enabling studies of capillary repair and dysfunction.
Proceedings of the National Academy of Sciences · May 18, 2026Peer-reviewedNeuroscience