Author

Srinivasarao Allu

University of PennsylvaniaORCID 0000-0002-6530-2582Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Sergei A. VinogradoviD· 3 shared Baoqiang LiiD· 2 shared Buyin Fu· 2 shared Cenk AyataiD· 2 shared Eng H. LoiD· 2 shared Ken AraiiD· 2 shared Sava SakadžićiD· 2 shared Anna DevoriD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Sergei A. VinogradovORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ECgo: All-Optical Induction of Single Endothelial Cell Injury and Capillary Occlusion in the Brain

Jacqueline Condrau, Srinivasarao Allu, Tatiana V. Esipova, Eva Erlebach, Matthias Tasso Wyss, Chaim Glück, Luca Ravotto, Thomas Troxler, Mikhail Drobizhev, Marco Villa, Paola Ceroni, Mohamad El Amki, Sergei A. Vinogradov, Bruno Weber

The paper introduces ECgo, an optical method to induce single endothelial cell injury and capillary occlusion in the mouse brain with high spatial precision, enabling studies of capillary repair and dysfunction.

Proceedings of the National Academy of Sciences · May 18, 2026Peer-reviewedNeuroscience

Global hypoperfusion leads to a mismatch in oxygen delivery and consumption in the cerebral watershed area

Baoqiang Li, Hewei Cao, Hajime Takase, Srinivasarao Allu, Yimeng Wu, Buyin Fu, Sergei A. Vinogradov, Ken Arai, Eng H. Lo, Cenk Ayata, Sava Sakadžić

This study investigates how global hypoperfusion affects oxygen delivery and consumption in the cerebral watershed area compared to the MCA territory using in vivo imaging techniques in mice.

bioRxiv · Jun 16, 2025 · PreprintNeuroscience

Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation

Paul Shin, Qi Pian, Hidehiro Ishikawa, Gen Hamanaka, Emiri T. Mandeville, Shuzhen Guo, Buyin Fu, Mohammed Ali H. Alfadhel, Srinivasarao Allu, İkbal Şencan, Baoqiang Li, Chongzhao Ran, Sergei A. Vinogradov, Cenk Ayata, Eng H. Lo, , Sava Sakadžić

This study shows aerobic exercise improves microvascular perfusion and oxygenation in deep brain regions of aged mice, correlating with better cognitive function.

eLife · Jun 19, 2023Peer-reviewedNeuroscience