Author

F. F. Twigg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

J. Geng· 2 shared M. Sato· 2 shared W. Cai· 2 shared W. Zhang· 2 shared A. Del Rio Flores· 1 shared A. M. Deutschbauer· 1 shared A. P. Arkin· 1 shared C. B. Eiben· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

J. Geng

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Total Biosynthesis of Triacsin Featuring an N-hydroxytriazene Pharmacophore

A. Del Rio Flores, F. F. Twigg, Y. Du, W. Cai, D. Q. Aguirre, M. Sato, M. J. Dror, M. Narayanamoorthy, J. Geng, N. A. Zill, W. Zhang

This study identifies the enzymes responsible for biosynthesizing the N-hydroxytriazene pharmacophore in triacsins, revealing two ATP-dependent enzymes involved in consecutive N-N bond formation.

bioRxiv · May 12, 2021Biochemistry

Massively parallel fitness profiling reveals multiple novel enzymes in Pseudomonas putida lysine metabolism

M. G. Thompson, J. M. Blake-Hedges, P. Cruz-Morales, J. F. Barajas, S. C. Curran, C. B. Eiben, N. C. Harris, V. T. Benites, J. W. Gin, W. A. Sharpless, F. F. Twigg, W. Skyrud, R. N. Krishna, J. H. Pereira, E. Baidoo, , J. D. Keasling

This paper uses RB-TnSeq to identify novel enzymes in Pseudomonas putida lysine metabolism, revealing new biochemical pathways and functions for DUF1338 proteins.

bioRxiv · Mar 18, 2019Microbiology

Identifying the Biosynthetic Gene Cluster for Triacsins with an N-hydroxytriazene Moiety

F. F. Twigg, W. Cai, W. Huang, J. Liu, M. Sato, T. Perez, J. Geng, M. Dror, I. Montanez, T. Tong, H. Lee, W. Zhang

This study identifies the biosynthetic gene cluster for triacsins in Streptomyces aureofaciens and discovers a new producer species.

bioRxiv · Dec 13, 2018Biochemistry