Author

F. G. Tafesse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Biochemistry· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 6 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Assay:imaging· 1 Assay:metabolomics· 1

Frequent Co-Authors

T. A. Bates· 4 shared E. Barklis· 3 shared H. C. Leier· 3 shared J. B. Weinstein· 3 shared S. K. McBride· 3 shared M. Trank-Greene· 2 shared S. E. Farley· 2 shared W. B. Messer· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersImmunology

T. A. Bates

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Trifunctional sphinganine: a new tool to dissect sphingolipid function

S. E. Farley, F. Stein, P. Haberkant, F. G. Tafesse, C. Schultz

The paper develops multifunctional derivatives of sphingosine and sphinganine to study their cellular roles, revealing distinct protein interactomes and spatiotemporal distributions.

bioRxiv · Oct 16, 2023Biochemistry

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages

T. A. Bates, M. Trank-Greene, X. Nguyenla, A. Anastas, S. Gurmessa, I. R. Merutka, S. D. Dixon, A. Shumate, A. R. Groncki, M. A. Parson, J. R. Ingram, E. Barklis, J. E. Burke, U. Shinde, H. L. Ploegh, F. G. Tafesse

This study investigates ESAT-6's self-association under acidic conditions and shows an ESAT-6-specific nanobody inhibits M. tuberculosis growth in macrophages.

bioRxiv · Aug 16, 2023Biochemistry

Diverging maternal and infant cord antibody functions from SARS-CoV-2 infection and vaccination in pregnancy

E. H. Adhikari, P. Lu, Y. J. Kang, A. R. McDonald, J. E. Pruszynski, T. A. Bates, S. K. McBride, M. Trank-Greene, F. G. Tafesse, L. L. Lu

This study compares maternal and infant cord antibody responses to SARS-CoV-2 infection and vaccination during pregnancy, finding differences in neutralizing activity, Fc effector functions, and glycosylation patterns.

bioRxiv · May 1, 2023Immunology

Delivery of loaded MR1 Monomer Results in Efficient Ligand Exchange to Host MR1 and Subsequent MR1T cell activation

C. A. Kulicke, G. M. Swarbrick, N. A. Ladd, M. Cansler, M. Null, A. Worley, C. Lemon, T. Ahmed, J. Bennett, T. N. Lust, C. M. Heisler, M. E. Huber, J. R. Krawic, L. M. Ankley, S. K. McBride, , M. J. Harriff

The paper demonstrates that delivering MR1 monomers loaded with 5-OP-RU enables ligand exchange to host MR1, leading to MR1T cell activation.

bioRxiv · Jul 11, 2022Immunology

A potent alpaca-derived nanobody that neutralizes SARS-CoV-2 variants

J. B. Weinstein, T. A. Bates, H. C. Leier, S. K. McBride, E. Barklis, F. G. Tafesse

This paper describes a potent alpaca-derived nanobody that neutralizes SARS-CoV-2 variants with high efficacy and stability.

bioRxiv · Jan 18, 2022Immunology

Cross-reactivity of SARS-CoV structural protein antibodies against SARS-CoV-2

T. A. Bates, J. B. Weinstein, S. E. Farley, H. C. Leier, W. B. Messer, F. G. Tafesse

This study evaluates cross-reactivity of SARS-CoV structural protein antibodies against SARS-CoV-2 and finds a high proportion of tested antibodies show cross-reactivity, suggesting potential utility in research and therapeutic development.

bioRxiv · Jul 30, 2020Immunology

A global lipid map defines a network essential for Zika virus replication

H. C. Leier, J. B. Weinstein, J. E. Kyle, J.-Y. Lee, L. M. Bramer, K. G. Stratton, D. Kempthorne, A. R. Navratil, E. G. Tafesse, T. Hornemann, W. B. Messer, E. A. Dennis, T. O. Metz, E. Barklis, F. G. Tafesse

This study identifies a sphingolipid metabolic network critical for Zika virus replication and shows ceramide flux mediates infection.

bioRxiv · Jan 27, 2020Microbiology

Sphingomyelin biosynthesis is essential for phagocytic signaling during Mycobacterium tuberculosis host cell entry

P. Niekamp, G. Guzman, H. Leier, A. Rashidfarrokhi, V. Richina, F. Pott, J. Holthuis, F. G. Tafesse

bioRxiv · Jul 12, 2019 · PreprintMicrobiology