Author

G. Guzman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:metabolomics· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. Cordoba-Chacon· 2 shared A. Diaz-Ruiz· 1 shared A. Pandey· 1 shared A. Rashidfarrokhi· 1 shared A. Terry· 1 shared B. Ramos-Molina· 1 shared B. T. Layden· 1 shared B. Wicksteed· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersPhysiology

J. Cordoba-Chacon

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Hepatocyte PPARγ contributes to the progression of non-alcoholic steatohepatitis in male and female obese mice.

S. M. Lee, J. Muratalla, S. Karimi, A. Diaz-Ruiz, D. Frutos, G. Guzman, B. Ramos-Molina, J. Cordoba-Chacon

This study shows that hepatocyte PPARγ contributes to NASH progression in obese mice and is linked to methionine metabolism and fibrosis.

bioRxiv · Jun 6, 2022Physiology

The hexokinase ''HKDC1'' interaction with the mitochondria is essential for hepatocellular carcinoma progression

M. W. Khan, A. Terry, M. Priyadarshini, G. Guzman, J. Cordoba-Chacon, I. Ben-Sahra, B. Wicksteed, B. T. Layden

This study shows that HKDC1's interaction with mitochondria is critical for HCC progression by altering metabolism and causing mitochondrial dysfunction.

bioRxiv · Nov 10, 2021 · PreprintCancer Biology

Phenylpropionc acid produced by gut microbiota alleviates acetaminophen-induced hepatotoxicity

S. Cho, K.-J. Won, X. Yang, V. Leone, E. B. Chang, E. Chung, J.-S. Park, G. Guzman, H. Lee, H. Jeong

This study shows that phenylpropionic acid from gut microbiota reduces acetaminophen-induced liver damage in mice by inhibiting the toxic enzyme CYP2E1.

bioRxiv · Jun 10, 2020 · PreprintPharmacology & Toxicology

Sphingomyelin biosynthesis is essential for phagocytic signaling during Mycobacterium tuberculosis host cell entry

P. Niekamp, G. Guzman, H. Leier, A. Rashidfarrokhi, V. Richina, F. Pott, J. Holthuis, F. G. Tafesse

bioRxiv · Jul 12, 2019 · PreprintMicrobiology

Opposing Roles of the Fork-head box genes FoxM1 and FoxA2 in Hepatocellular Carcinoma

P. Raychaudhuri, V. Chand, A. Pandey, D. Kopanja, G. Guzman

This paper shows FoxM1 promotes hepatocellular carcinoma by repressing FoxA2, which in turn inhibits FoxM1 and suppresses tumor progression.

bioRxiv · Aug 2, 2018 · PreprintCancer Biology