Author

F. Loayza-Puch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

E. Stepanova· 2 shared A. Hedley· 1 shared A. J. R. Heck· 1 shared A. Jeko· 1 shared B. Nicolet· 1 shared C. Boldrini· 1 shared C. F. Calkhoven· 1 shared C. Jamieson· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

E. Stepanova

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Oncogenic functions of the m6A demethylase FTO in breast cancer cells involving translational upregulation of C/EBPβ-LIP

H. R. Zuidhof, C. Müller, G. Kortman, R. Wardenaar, E. Stepanova, F. Loayza-Puch, C. F. Calkhoven

This study shows FTO promotes oncogenic functions in TNBC by regulating C/EBPβ-LIP translation, which drives EMT and metastasis.

bioRxiv · Sep 21, 2023 · PreprintCancer Biology

Gene and protein sequence features augment HLA class I ligand predictions

K. Bresser, B. Nicolet, A. Jeko, W. Wu, F. Loayza-Puch, R. Agami, A. J. R. Heck, M. J. R. Wolkers, T. Schumacher

The paper evaluates gene and protein sequence features as predictors of HLA class I ligand presentation, showing they improve predictions comparable to experimental gene expression data.

bioRxiv · Sep 3, 2023Immunology

PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix

E. J. Kay, K. Paterson, C. Riero Domingo, D. Sumpton, H. Daebritz, S. Tardito, C. Boldrini, J. R. Hernandez-Fernaud, D. Athineos, S. Dhayade, E. Stepanova, E. Gjerga, L. J. Neilson, S. Lilla, A. Hedley, , S. Zanivan

This study identifies PYCR1-dependent proline synthesis in cancer-associated fibroblasts as critical for collagen production and tumor progression, suggesting PYCR1 as a therapeutic target to inhibit pro-tumorigenic extracellular matrix deposition.

bioRxiv · May 30, 2020 · PreprintCancer Biology