Lysosomal membrane permeabilization enhances the anticancer effects of RNA Polymerase I transcription inhibitors
Lucille Ferret, Jonathan G. Pol, Allan Sauvat, Gautier Stoll, Karla Alvarez-Valadez, Alexandra Müller, Julie Le Naour, F. Peyre, Gerasimos Anagnostopoulos, Isabelle Martins, Maria Chiara Maiuri, Harald Wodrich, Lionel Guittat, Jean‐Louis Mergny, Guido Kroemer, Mojgan Djavaheri‐Mergny
This study shows that lysosomal membrane permeabilization enhances the effectiveness of RNA Polymerase I inhibitors against cancer cells.
Autophagy · Jun 18, 2025Peer-reviewedCancer Biology