Simultaneous LC-MS determination of glucose regulatory peptides secreted by stem cell-derived islet organoids
C. Olsen, C. Wang, A. Aizenshtadt, S. Abadpour, E. Lundanes, F. S. Skottvoll, A. Golovin, M. Busek, S. Krauss, H. Scholz, S. R. Wilson
The paper develops an RPLC-MS/MS method to simultaneously measure insulin, somatostatin-14, and glucagon from stem cell-derived islet organoids on an organ-on-chip platform, showing functional hormone secretion.
ELECTROPHORESIS · Aug 13, 2023Peer-reviewedBiochemistry