Author

S. R. Wilson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 4 Research Focus:drug response / drug discovery· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

E. Lundanes· 5 shared F. S. Skottvoll· 5 shared A. Aizenshtadt· 4 shared S. Krauss· 4 shared H. Scholz· 3 shared I. L. Bogen· 3 shared C. Olsen· 2 shared C. Wang· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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5 shared papersBiochemistry

E. Lundanes

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Simultaneous LC-MS determination of glucose regulatory peptides secreted by stem cell-derived islet organoids

C. Olsen, C. Wang, A. Aizenshtadt, S. Abadpour, E. Lundanes, F. S. Skottvoll, A. Golovin, M. Busek, S. Krauss, H. Scholz, S. R. Wilson

The paper develops an RPLC-MS/MS method to simultaneously measure insulin, somatostatin-14, and glucagon from stem cell-derived islet organoids on an organ-on-chip platform, showing functional hormone secretion.

ELECTROPHORESIS · Aug 13, 2023Peer-reviewedBiochemistry

Mass Spectrometry Reveals that Oxysterols are Secreted from Non-Alcoholic Fatty Liver Disease Induced Organoids

K. S. Komurcu, I. Wilhelmsen, J. L. Thorne, S. Krauss, S. R. Wilson, A. Aizenshtadt, H. Roberg-Larsen

The paper uses mass spectrometry to show that liver organoids secrete oxysterols, with 26-hydroxycholesterol being elevated in steatotic organoids and potentially acting as a biomarker for NAFLD.

bioRxiv · Feb 22, 2023Biochemistry

Determination of insulin secretion from stem cell-derived islets with liquid chromatography-tandem mass spectrometry

C. Olsen, C. Wang, S. Abadour, E. Lundanes, A. S. Hansen, F. S. Skottvoll, H. Scholz, S. R. Wilson

The paper develops a sensitive and selective RPLC-MS/MS method to quantify insulin secretion from islet organoids, overcoming carry-over and sensitivity issues with low-volume samples.

Journal of Chromatography B · Jan 1, 2023Peer-reviewedBioengineering

Scalable production of tissue-like vascularised liver organoids from human PSCs.

S. P. Harrison, R. Sillar, Y. Tanaka, Y. Xiang, B. Patterson, H. Kempf, E. Melum, K. Asrud, M. E. Chollet, E. Andersen, P. M. Sandset, S. Baumgarten, F. Bonanini, D. Kurek, S. Mathapati, , G. J. Sullivan

This paper develops a method to produce vascularised liver organoids from human PSCs without 2D patterning or ECM, demonstrating liver-like functions and cellular complexity.

bioRxiv · Dec 2, 2020 · PreprintCell Biology

"Organoid-in-a-column" coupled on-line with liquid chromatography-mass spectrometry

S. Kogler, A. Aizenshtadt, S. Harrison, F. S. Skottvoll, H. E. Berg, S. Abadpour, H. Scholz, G. Sullivan, B. Thiede, E. Lundanes, I. L. Bogen, S. Krauss, H. Roberg-Larsen, S. R. Wilson

This paper demonstrates the integration of liver organoids with liquid chromatography-mass spectrometry for on-line drug metabolism analysis.

bioRxiv · Sep 8, 2020Bioengineering

Searching for a UV-filter in the eyes of high flying birds

M. Zawadzka, B. Racz, D. Ambrosini, C. H. Gorbitz, J. P. Morth, E. Lundanes, F. Rise, A. Ringvold, S. R. Wilson, A. Wilkins, K. B. Presto Elgstoen, A. Osteby

The study investigates a UV-absorbing compound in high-flying birds' aqueous humor but fails to identify the UV-protective compound 'X' using spectroscopic methods.

bioRxiv · Jun 23, 2020 · PreprintBiochemistry

Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies

F. S. Skottvoll, F. Hansen, S. Harrison, I. C. S. Boger, A. Mrsa, M. S. Restan, M. Stein, E. Lundanes, S. Pedersen-Bjergaard, A. Aizenshtadt, S. Krauss, G. J. Sullivan, I. L. Bogen, S. R. Wilson

This study demonstrates the use of electromembrane extraction (EME) combined with mass spectrometry to monitor drug metabolism in liver organoids.

bioRxiv · May 15, 2020Biochemistry