Engineered small extracellular vesicles as a FGL1/PD-L1 dual-targeting delivery system for alleviating immune rejection
H.-i. Tsai, Y. Wu, X. Liu, Z. Xu, L. Liu, Y. Huang, L. Wang, W. Zhang, H. Zhang, D. Su, F. U. Khan, C. Wang, J. E. Eriksson, B. Jia, F. Cheng, H. Chen
This study develops engineered small extracellular vesicles targeting FGL1 and PD-L1 to suppress immune rejection in transplantation by inhibiting T cell activation and improving graft survival.
Advanced Science · Nov 5, 2021Peer-reviewedBioengineering