B. Jia

Substrate profiling of human Transglutaminase 1 using cDNA display and next-generation sequencing

This study identifies substrate preferences of human transglutaminase 1 using cDNA display and next-generation sequencing, revealing a high-reactivity peptide and potential new substrates.

Biological condensates form percolated networks with molecular motion properties distinctly different from dilute solutions

This study develops a single molecule imaging method to analyze molecular motion in biological condensates, revealing distinct motion behaviors compared to dilute solutions.

SnRK2-mediated phosphorylation of SIZ1 enhances global SUMOylation under osmotic stress in Arabidopsis

This study identifies SnRK2-mediated phosphorylation of SIZ1 as a mechanism enhancing SUMOylation under osmotic stress in Arabidopsis.

Phase separation-mediated actin bundling by the postsynaptic density condensates

This study shows that PSD condensates mediate actin bundling through phase separation, involving Homer and other scaffolds, and is regulated by CaMKII and Homer1a.

Discovery of aphid-transmitted Rice tiller inhibition virus from native plants through metagenomic sequencing

The paper discovers a new aphid-transmitted rice virus, RTIV, from wild rice plants and shows it causes low-tillering disease in rice cultivars.

Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor

This study investigates whether enhancing natriuretic peptide signaling in skeletal muscle improves exercise performance in mice, finding no significant improvement in knockout mice.

Fast and specific enrichment of cancer-related exosomes by DNA-nanoweight-assisted centrifugation

This paper introduces a method to efficiently enrich cancer-related exosomes using DNA-tetrahedron nanoweights, achieving high sensitivity and specificity in clinical samples.

cDNA display coupled with next-generation sequencing for rapid activity-based screening: Comprehensive analysis of transglutaminase substrate preference

The paper develops a cDNA display combined with next-generation sequencing platform to analyze transglutaminase 2 substrate preferences, revealing comprehensive amino acid preferences at specific peptide positions.

Engineered small extracellular vesicles as a FGL1/PD-L1 dual-targeting delivery system for alleviating immune rejection

This study develops engineered small extracellular vesicles targeting FGL1 and PD-L1 to suppress immune rejection in transplantation by inhibiting T cell activation and improving graft survival.

Open Source ImmGen: network perspective on metabolic diversity among mononuclear phagocytes

The paper analyzes metabolic diversity in mononuclear phagocytes across tissues using integrated datasets and a network-based approach, identifying key metabolic subnetworks and their functional roles.

First Draft Genome Sequence of the Pathogenic Fungus Lomentospora prolificans (formerly Scedosporium prolificans)

The paper reports the first draft genome sequence of Lomentospora prolificans, assembled using Illumina and Oxford Nanopore reads, resulting in a highly contiguous genome with 8,656 protein-coding genes.