CRISPR/Cas9-based edition of frataxin gene in Dictyostelium discoideum for Friedreich's Ataxia disease modeling
H. G. Gentili, M. F. Pignataro, J. Olmos, M. F. Pavan, L. I. Ibanez, J. Santos, F. Velazquez
This paper develops a Dictyostelium discoideum model for Friedreich's Ataxia by editing the fxn locus and assessing the effects of a human variant.
bioRxiv · Feb 27, 2023 · PreprintCell Biology