Author

M. F. Pavan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:Drosophila· 1 Research Focus:protein folding & dynamics· 1 Organism:yeast· 1

Frequent Co-Authors

L. I. Ibanez· 4 shared J. Santos· 3 shared M. F. Pignataro· 3 shared A. D. Nadra· 2 shared A. M. Zelada· 2 shared Argentinian AntiCovid Consortium· 2 shared C. D'Alessio· 2 shared C. H. Pavan· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBiochemistry

L. I. Ibanez

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nanobodies against SARS-CoV-2 reduced virus load in the brain of challenged mice and neutralized Wuhan, Delta and Omicron Variants

M. F. Pavan, M. Bok, R. Betanzos San Juan, J. P. Malito, G. A. Marcoppido, D. R. Franco, D. A. Militello, J. M. Schammas, S. Bari, W. B. Stone, K. Lopez, D. Porier, J. Muller, A. J. Auguste, L. Yuan, , L. I. Ibanez

This study develops nanobodies against SARS-CoV-2 that neutralize multiple variants and reduce viral load in the brain of infected mice.

bioRxiv · Mar 14, 2023 · PreprintImmunology

CRISPR/Cas9-based edition of frataxin gene in Dictyostelium discoideum for Friedreich's Ataxia disease modeling

H. G. Gentili, M. F. Pignataro, J. Olmos, M. F. Pavan, L. I. Ibanez, J. Santos, F. Velazquez

This paper develops a Dictyostelium discoideum model for Friedreich's Ataxia by editing the fxn locus and assessing the effects of a human variant.

bioRxiv · Feb 27, 2023 · PreprintCell Biology

Production of a Highly Immunogenic Antigen from SARS-CoV-2 by Covalent Coupling of the Receptor Binding Domain of Spike Protein to a Multimeric Carrier

Argentinian AntiCovid Consortium, P. M. Berguer, M. Blaustein, L. Bredeston, P. O. Craig, C. D'Alessio, F. Elias, P. C. Farre, N. B. Fernandez, H. G. Gentili, Y. Gandola, J. Gasulla, G. E. Gudesblat, M. G. Herrera, L. I. Ibanez, , A. M. Zelada

This paper shows that coupling multiple SARS-CoV-2 RBD units to a multimeric carrier protein enhances immune response, leading to higher neutralizing antibody titers.

bioRxiv · Apr 25, 2021 · PreprintBiochemistry

Structural and Functional Comparison of SARS-CoV-2-Spike Receptor Binding Domain Produced in Pichia pastoris and Mammalian Cells

Argentinian AntiCovid Consortium, C. R. Arbeitman, G. Auge, M. Blaustein, L. Bredeston, E. S. Corapi, P. O. Craig, L. A. Cossio, L. Dain, C. D'Alessio, F. Elias, N. B. Fernandez, J. Gasulla, N. Gorojovsky, G. E. Gudesblat, , A. M. Zelada

This study compares the structural and functional properties of SARS-CoV-2 Spike RBD produced in yeast and mammalian cells, finding similar stability but greater heterogeneity in yeast-produced RBD.

bioRxiv · Sep 17, 2020 · PreprintBiochemistry