Author

Fatoumatta Sisay-Joof

MRC Unit the Gambia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 4 Organism:human· 4 Approach:statistical model· 4 Assay:whole-genome sequencing· 3 Research Focus:benchmarking· 1 Assay:GWAS summary statistics· 1 Organism:plant (other)· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anna E. JeffreysiD· 4 shared Carolyne NdilaiD· 4 shared Christina HubbartiD· 4 shared David J. ConwayiD· 4 shared Dominic P. KwiatkowskiiD· 4 shared Ellen Miranda LeffleriD· 4 shared Gavin BandiD· 4 shared Kalifa BojangiD· 4 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetics

Anna E. JeffreysORCID

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4 papers

Recent·Most cited

Large-scale genotyping and meta-analysis of PIEZO1 short tandem repeat alleles suggest a modest association with malaria susceptibility

Ellen Miranda Leffler, Gavin Band, Anna E. Jeffreys, Kate Rowlands, Christina Hubbart, Kalifa Bojang, David J. Conway, Muminatou Jallow, Fatoumatta Sisay-Joof, Umberto D’Alessandro, Carolyne Ndila, Alexander W. Macharia, Kevin Marsh, Thomas Neil Williams, David Kachala, , Dominic P. Kwiatkowski

The paper genotypes PIEZO1 STR alleles in malaria cases and controls, finding a modest protective effect of E756del against malaria.

bioRxiv · Jun 12, 2024 · PreprintGenetics

The protective effect of sickle cell haemoglobin against severe malaria depends on parasite genotype

Gavin Band, Ellen Miranda Leffler, Muminatou Jallow, Fatoumatta Sisay-Joof, Carolyne Ndila, Alexander W. Macharia, Christina Hubbart, Anna E. Jeffreys, Kate Rowlands, Thuy Nguyen, Sónia Gonçalves, Cristina V. Ariani, Jim Stalker, Richard D. Pearson, Roberto Amato, , Dominic P. Kwiatkowski

The paper investigates the association between host sickle cell haemoglobin and parasite genetic variation in malaria severity, finding that parasite alleles linked to HbS show strong linkage disequilibrium and frequency covariation with HbS.

Nature · Dec 9, 2021Peer-reviewedGenetics

New insights into malaria susceptibility from the genomes of 17,000 individuals from Africa, Asia, and Oceania

Malaria Genomic Epidemiology Network, Gavin Band, Si Quang Le, Geraldine M Clarke, Katja Kivinen, Christina Hubbart, Anna E. Jeffreys, Kate Rowlands, Ellen Miranda Leffler, Muminatou Jallow, David J. Conway, Fatoumatta Sisay-Joof, Giorgio Sirugo, Umberto D’Alessandro, Ousmane Touré, , Dominic P. Kwiatkowski

This study identifies five genome-wide associations with severe malaria risk in 17,000 individuals from Africa, Asia, and Oceania, including a new variant linked to cerebral malaria.

Nature Communications · Dec 16, 2019Peer-reviewedGenetics

Resistance to malaria through structural variation of red blood cell invasion receptors

Ellen Miranda Leffler, Gavin Band, George Busby, Katja Kivinen, Si Quang Le, Geraldine M Clarke, Kalifa Bojang, David J. Conway, Muminatou Jallow, Fatoumatta Sisay-Joof, Edith C. Christiane Bougouma, Valentina Dianora Mangano, David Modiano, Sodiomon Bienvenu Sirima, Eric Akum Achidi, , Malaria Genomic Epidemiology Network

The paper identifies a structural variant in GYPA and GYPB genes associated with reduced risk of severe malaria in sub-Saharan African populations.

Science · May 18, 2017Peer-reviewedGenomics