Anna E. Jeffreys

This paper develops a targeted genomic surveillance approach for insecticide resistance in malaria vectors, identifying resistance variants and demonstrating predictive modeling with high accuracy.

The paper genotypes PIEZO1 STR alleles in malaria cases and controls, finding a modest protective effect of E756del against malaria.

This paper introduces a cost-effective targeted nanopore sequencing approach for P. falciparum genomic surveillance, validated with mock and field samples.

The paper investigates the association between host sickle cell haemoglobin and parasite genetic variation in malaria severity, finding that parasite alleles linked to HbS show strong linkage disequilibrium and frequency covariation with HbS.

The paper analyzes genome variation in 1,142 Anopheles mosquitoes to study population structure and insecticide resistance.

This study identifies five genome-wide associations with severe malaria risk in 17,000 individuals from Africa, Asia, and Oceania, including a new variant linked to cerebral malaria.

The paper sequences genomes of 765 malaria vector mosquitoes to study genetic diversity and insecticide resistance.

The paper identifies a structural variant in GYPA and GYPB genes associated with reduced risk of severe malaria in sub-Saharan African populations.