Jim Stalker

The protective effect of sickle cell haemoglobin against severe malaria depends on parasite genotype

The paper investigates the association between host sickle cell haemoglobin and parasite genetic variation in malaria severity, finding that parasite alleles linked to HbS show strong linkage disequilibrium and frequency covariation with HbS.

Genome variation and population structure among 1,142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii

The paper analyzes genome variation in 1,142 Anopheles mosquitoes to study population structure and insecticide resistance.

New insights into malaria susceptibility from the genomes of 17,000 individuals from Africa, Asia, and Oceania

This study identifies five genome-wide associations with severe malaria risk in 17,000 individuals from Africa, Asia, and Oceania, including a new variant linked to cerebral malaria.

Natural diversity of the malaria vector Anopheles gambiae

The paper sequences genomes of 765 malaria vector mosquitoes to study genetic diversity and insecticide resistance.

Resistance to malaria through structural variation of red blood cell invasion receptors

The paper identifies a structural variant in GYPA and GYPB genes associated with reduced risk of severe malaria in sub-Saharan African populations.

Genomic epidemiology of the current wave of artemisinin resistant malaria

This study identifies kelch13 mutations associated with artemisinin resistance in Southeast Asia and finds low frequency of these mutations in Africa, suggesting different evolutionary pressures.