Author

Federico Cutrupi

King Abdullah University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandro AlaimoiD· 1 shared Alessandro RomaneliD· 1 shared Alessandro VasciaveoiD· 1 shared Andrea LunardiiD· 1 shared Arianna MangiavacchiiD· 1 shared Armin Niksic· 1 shared Chandra Shekhar VermaiD· 1 shared Dario De FeliceiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Alessandro AlaimoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Histone Succinylation-Driven LINE-1 Reactivation Links High-Fat Diet Stress to Hepatic Inflammation and Liver Disease

Reem Daouk, Federico Cutrupi, Peng Liu, Arianna Mangiavacchi, Francesco Della Valle, Gabriele Morelli, Marco D'Onghia, Armin Niksic, Meritxell Huch, Valerio Orlando

This study shows high-fat diet stress reactivates LINE-1 elements via histone succinylation, causing inflammation and liver disease, and suggests L1 inhibition as a therapeutic approach.

bioRxiv · Dec 19, 2025 · PreprintMolecular Biology

Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer

Dario De Felice, Alessandro Alaimo, Davide Bressan, Sacha Genovesi, Elisa Marmocchi, Nicole Annesi, Giulia Beccaceci, Davide Dalfovo, Federico Cutrupi, Stefano Medaglia, Veronica Foletto, Marco Lorenzoni, Francesco Gandolfi, Srinivasaraghavan Kannan, Chandra Shekhar Verma, , Andrea Lunardi

This study shows RA signaling promotes luminal identity in prostate progenitors through Foxa1, and identifies a loss-of-function mutation in Foxa1 linked to prostate cancer dedifferentiation.

EMBO Reports · Dec 4, 2024Peer-reviewedCancer Biology