Distinct ATRX functions cooperate with 9-1-1 and CST complexesto safeguard replication and telomere integrity
Sandra Segura‐Bayona, Marija Maric, Tohru Takaki, Zornitsa Manova, Tyler H. Stanage, Aurora Irene Idilli, Graeme Hewitt, Feras E. Machour, Rhona Millar, Marek Adamowicz, Ronnie Ren Jie Low, Phil Ruis, Benura Azeroglu, Todd Fallesen, Harshil Patel, , Simon J. Boulton
This study identifies distinct roles of ATRX in safeguarding genome and telomere integrity through interactions with CST and 9-1-1 complexes, revealing context-dependent mechanisms.
Nature Structural & Molecular Biology · Jun 30, 2026Peer-reviewedMolecular Biology