Aurora Irene Idilli

The paper shows MEN1 deficiency reduces ferroptosis by altering ACSL1 and GPX4 levels, with selenite affecting resistance.

This study identifies distinct roles of ATRX in safeguarding genome and telomere integrity through interactions with CST and 9-1-1 complexes, revealing context-dependent mechanisms.

The paper identifies a covalent fragment inhibitor of TYMS that selectively kills ATRX-deficient cells through replication stress.

This paper identifies SLFN11's role in preventing alternative lengthening of telomeres by eliminating ATRX-deficient cells during telomere crisis, contributing to chemoresistance in cancer.

This study shows that telomeric antisense oligonucleotides reduce premature aging in telomerase mutant zebrafish by inhibiting DDR signaling.