G. Bahcecioglu

Aged Breast Matrix Bound Vesicles Promote Breast Cancer Invasiveness

This study identifies aged breast matrix-bound vesicles (MBVs) that promote cancer invasiveness by altering miRNA and cytokine profiles in human mammary epithelial cells.

Maternal obesity driven changes in collagen linearity of breast extracellular matrix induces invasive mammary epithelial cell phenotype

This study shows that maternal obesity alters breast extracellular matrix collagen structure, increasing mammary epithelial cell migration and invasion.

Age and Sex-Dependent Differences in Human Cardiac Matrix-Bound Exosomes Modulate Fibrosis through Synergistic miRNA Effects

This study identifies age and sex differences in cardiac matrix-bound exosomes and shows their synergistic miRNA effects on fibrosis.

Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer-Like Phenotype

This study shows that aged breast ECM drives mammary epithelial cells to an invasive, cancer-like phenotype through mechanisms involving EMT and LOX.

Effect of Cellular and ECM Aging on Human iPSC-derived Cardiomyocyte Performance, Maturity and Senescence

This study examines how cellular and ECM aging affect iPSC-derived cardiomyocyte function, maturity, and stress response, finding that ECM aging accelerates cellular aging and impairs cardiac function.

Tissue failure propagation as mediated by circulatory flow

The paper investigates how cell failure propagates in synthetic tissues under advective flow, finding analytical expressions for propagation dynamics.

Anatomical meniscus construct with zone specific biochemical composition and structural organization

The paper engineers a meniscus-like scaffold with zone-specific biochemical and structural properties, showing enhanced collagen production and cell alignment.