Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer-Like Phenotype
G. Bahcecioglu, X. Yue, E. Howe, I. Guldner, M. S. Stack, H. Nakshatri, S. Zhang, P. Zorlutuna
This study shows that aged breast ECM drives mammary epithelial cells to an invasive, cancer-like phenotype through mechanisms involving EMT and LOX.
bioRxiv · Sep 30, 2020Cancer Biology