A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma
D. C. Farhat, M. W. Bowler, G. Communie, D. PONTIER, L. Belmudes, C. MAS, C. Corrao, Y. COUTE, A. BOUGDOUR, T. LAGRANGE, M.-a. HAKIMI, C. Swale
This paper identifies an m6A-dependent polyadenylation mechanism in Toxoplasma gondii that prevents transcriptional read-through and maintains transcriptome integrity, similar to a plant mechanism.
bioRxiv · Feb 23, 2021Microbiology