Diffusion of activated ATM explains γH2AX and MDC1 spread beyond the DNA damage site
G. Danovski, G. Panova, B. Keister, G. Georgiev, K. B. Blagoev, S. Stoynov
The paper measures ATM and MDC1 recruitment kinetics at DNA lesions and proposes activated ATM diffusion as the mechanism for MDC1 spread beyond the damage site.
bioRxiv · Oct 2, 2023Cell Biology