Author

D. Lefteri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

C. S. McKimmie· 2 shared A. C. Kalli· 1 shared A. Kohl· 1 shared A. Macdonald· 1 shared A. Merits· 1 shared A. Moran· 1 shared C. Donald· 1 shared C. McNamara· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

C. S. McKimmie

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3 papers

Recent·Most cited

Wolbachia strain wAu differs in cellular perturbation and virus inhibition profiles from previously characterised Wolbachia strains

S. Rainey, V. Geoghegan, D. Lefteri, T. Ant, J. Martinez, C. McNamara, S. P. Sinkins

This study compares the cellular perturbation and antiviral profiles of Wolbachia strain wAu with other strains, finding unique features in its virus inhibition mechanisms.

bioRxiv · Sep 2, 2021 · PreprintMicrobiology

Inhibitors of the Small Membrane (M) Protein Viroporin Prevent Zika Virus Infection

E. Brown, G. Swinscoe, D. Lefteri, R. Singh, A. Moran, R. Thompson, D. Maskell, H. Beaumont, M. J. Bentham, C. Donald, A. Kohl, A. Macdonald, N. Ranson, R. Foster, C. S. McKimmie, , S. C. Griffin

This study identifies the ZIKV M protein as a therapeutic target, showing that inhibitors like rimantadine block viral infection in vitro and in vivo by targeting M-formed channels.

bioRxiv · Mar 11, 2021Microbiology

Mosquito saliva sialokinin-dependent enhancement of arbovirus infection through endothelial barrier leakage

D. Lefteri, S. Bryden, M. Pingen, S. Terry, E. Beswick, G. Georgiev, M. Van Der Laan, V. Mastrullo, P. Campagnolo, R. M. Waterhouse, M. Varjak, A. Merits, R. Fragkoudis, S. Griffin, E. Pondeville, C. S. McKimmie

This study identifies sialokinin in Aedes mosquito saliva as a factor that enhances arbovirus infection by reducing endothelial barrier integrity, suggesting it as a therapeutic target.

bioRxiv · Feb 19, 2021Microbiology