Author

G. Gerlitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

L. Kaczmarczyk· 2 shared M. Salmon-Divon· 2 shared N. Levi· 2 shared A. Burgess· 1 shared A. D. Stephens· 1 shared A. Zhu· 1 shared B. Anderson· 1 shared C. Capistran· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

L. Kaczmarczyk

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Author profile →

5 papers

Recent·Most cited

CTCF is essential for proper mitotic spindle structure and anaphase segregation

K. Chiu, Y. Berrada, N. Eskndir, D. Song, C. Fong, S. Naughton, T. Chen, S. Moy, S. Gyurmey, L. James, C. Ezeiruaku, C. Capistran, D. Lowey, V. Diwanji, S. Peterson, , A. D. Stephens

This study shows that CTCF is crucial for correct mitotic spindle structure and anaphase segregation, leading to abnormal nuclear morphology in interphase.

bioRxiv · Jan 9, 2023Cell Biology

Evolution of resistance to Irinotecan in cancer cells involves generation of topoisomerase-guided mutations in non-coding genome that reduce the chances of DNA breaks

S. Kumar, V. Gahramanov, S. Patel, J. Yaglom, L. Kaczmarczyk, I. Alexandrov, G. Gerlitz, M. Salmon-Divon, M. Y. Sherman

The paper investigates how cancer cells develop resistance to irinotecan by generating topoisomerase-guided mutations in non-coding regions, reducing DNA breaks and increasing drug resistance.

bioRxiv · Nov 26, 2021Cancer Biology

SETDB1 regulates microtubule dynamics

R. Hernandez-Vicens, N. Pernicone, T. Listovsky, G. Gerlitz

This study shows SETDB1 regulates microtubule dynamics through a methylation-independent mechanism involving interaction with HDAC6 and tubulin deacetylation.

bioRxiv · May 15, 2021Cell Biology

Nuclear lamin A/C promotes cancer cell survival and lung metastasis without restricting transendothelial migration

F. Roncato, O. Regev, S. W. Feigelson, S. K. Yadav, L. Kaczmarczyk, N. Levi, D. Drago-Garcia, S. Ovadia, M. Kizner, Y. Addadi, J. C. Sabino, Y. Ovadya, S. F. de Almeida, E. Feldmesser, G. Gerlitz, R. Alon

Cancers · May 14, 2021Peer-reviewedCancer Biology

The heterochromatin landscape in migrating cells and the importance of H3K27me3 for migration-associated transcriptional changes

T. Segal, M. Salmon-Divon, G. Gerlitz

The paper maps epigenetic markers in migrating cells and finds H3K27me3 is critical for migration-associated transcriptional changes.

bioRxiv · Jun 12, 2018Cell Biology