Author

G. H. Babunovic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. M. Fortune· 4 shared J. G. Doench· 2 shared L. Cui· 2 shared T. K. Lu· 2 shared Y. Lai· 2 shared A. K. Shalek· 1 shared A. Nibasumba· 1 shared B. B. Aldridge· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersMicrobiology

S. M. Fortune

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tuberculosis treatment failure associated with evolution of antibiotic resilience

Q. Liu, J. Zhu, C. L. Dulberger, S. Stanley, S. Wilson, E. S. Chung, X. Wang, P. Culviner, Y. J. Liu, N. D. Hicks, G. H. Babunovic, S. R. Giffen, B. B. Aldridge, E. C. Garner, E. J. Rubin, , S. M. Fortune

The paper identifies resR as a target of positive selection in Mtb clinical isolates, linking its mutations to antibiotic resilience and treatment failure.

bioRxiv · Mar 29, 2022Microbiology

GM-CSF differentiation of human monocytes stabilizes macrophage state via oxidative signaling

C. Y. Itoh, C. Gunnarson, G. H. Babunovic, A. Nibasumba, N. A. Akilimali, M. H. Wadsworth, T. H. Hughes, S. L. Solomon, B. Hie, B. Berger, A. K. Shalek, S. M. Fortune, B. D. Bryson

This study shows that GM-CSF differentiation of human monocytes reduces IL-10 production through oxidative signaling, highlighting its role in macrophage function and plasticity.

bioRxiv · Sep 29, 2020 · PreprintImmunology

High-throughput CRISPR screens to dissect macrophage-Shigella interactions

Y. Lai, L. Cui, G. H. Babunovic, S. M. Fortune, J. G. Doench, T. K. Lu

This study uses CRISPR screens to identify host factors involved in Shigella-induced inflammation and macrophage survival, revealing potential therapeutic targets.

bioRxiv · Apr 25, 2020Microbiology

Illuminating host-mycobacterial interactions with functional genomic screening to inhibit mycobacterial pathogenesis

Y. Lai, G. H. Babunovic, L. Cui, P. C. Dedon, J. G. Doench, S. M. Fortune, T. K. Lu

This study uses CRISPR screens to identify host genes that inhibit mycobacterial growth, revealing potential targets for host-directed tuberculosis therapies.

bioRxiv · Mar 30, 2020Microbiology