Author

G. J. Overheul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:Arabidopsis· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

R. P. Van Rij· 5 shared B. Besson· 2 shared J. Qu· 2 shared M. Vermeulen· 2 shared P. Miesen· 2 shared A. van Laarhoven· 1 shared C. G. Spruijt· 1 shared D. J. Obbard· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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5 shared papersMicrobiology

R. P. Van Rij

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5 papers

Recent·Most cited

Pan-flavivirus analysis reveals sfRNA-independent, 3'UTR-biased siRNA production from an Insect-Specific Flavivirus

B. Besson, G. J. Overheul, M. T. Wolfinger, S. Junglen, R. P. Van Rij

The paper compares siRNA profiles of mosquito-borne and insect-specific flaviviruses, finding 3'UTR-biased siRNA production in insect-specific viruses like Kamiti River virus, independent of sfRNA.

Journal of Virology · Nov 19, 2024Peer-reviewedMicrobiology

The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells

J. Qu, M. Schinkel, L. Chiggiato, S. Rosendo Machado, G. J. Overheul, P. Miesen, R. P. van Rij

The paper identifies the Hsf1-sHsp cascade as a pan-antiviral mechanism in mosquito cells, effective against multiple arboviruses.

bioRxiv · Feb 21, 2023Microbiology

Arbovirus-vector protein interactomics identifies Loquacious as a co-factor for dengue virus replication in Aedes mosquitoes

B. Besson, O. M. Lezcano, G. J. Overheul, K. Janssen, C. G. Spruijt, M. Vermeulen, J. Qu, R. P. Van Rij

The paper identifies Loquacious as a mosquito host factor essential for dengue and Zika virus replication, revealing its role in viral RNA replication independent of RNAi activity.

bioRxiv · Feb 4, 2022Microbiology

Berberine and obatoclax inhibit SARS-CoV-2 replication in primary human nasal epithelial cells in vitro

F. S. Varghese, E. van Woudenbergh, G. J. Overheul, M. J. Eleveld, L. Kurver, N. van Heerbeek, A. van Laarhoven, P. Miesen, G. den Hartog, M. I. de Jonge, R. P. van Rij

bioRxiv · Dec 23, 2020Microbiology

Induction and suppression of NF-κB signalling by a DNA virus of Drosophila

W. H. Palmer, J. Joosten, G. J. Overheul, P. W. Jansen, M. Vermeulen, D. J. Obbard, R. P. Van Rij

This study investigates how a Drosophila DNA virus, Kallithea virus, interacts with the insect immune system, identifying gp83 as a Toll pathway inhibitor.

bioRxiv · Jun 29, 2018Microbiology