Author

C. G. Spruijt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:Arabidopsis· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. Vermeulen· 3 shared A. B. van Spriel· 1 shared A. C. O. Vertegaal· 1 shared A. Kragten· 1 shared A. Rodgers Furones· 1 shared A. van Duffelen· 1 shared B. Besson· 1 shared D. van den Heuvel· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCell Biology

M. Vermeulen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells

R. Santalla Mendez, A. Rodgers Furones, R. Classens, M. Haverdil, M. Canela Capdevila, A. van Duffelen, M. ter Beest, C. G. Spruijt, M. Vermeulen, A. B. van Spriel, L. Querol Cano

This study identifies galectin-9 as essential for cytokine trafficking in dendritic cells by interacting with Vamp-3, preventing cytokine accumulation in the Golgi and promoting secretion.

bioRxiv · May 13, 2022 · PreprintCell Biology

Arbovirus-vector protein interactomics identifies Loquacious as a co-factor for dengue virus replication in Aedes mosquitoes

B. Besson, O. M. Lezcano, G. J. Overheul, K. Janssen, C. G. Spruijt, M. Vermeulen, J. Qu, R. P. Van Rij

The paper identifies Loquacious as a mosquito host factor essential for dengue and Zika virus replication, revealing its role in viral RNA replication independent of RNAi activity.

bioRxiv · Feb 4, 2022Microbiology

A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair

D. van den Heuvel, C. G. Spruijt, R. Gonzalez-Prieto, A. Kragten, M. T. Paulsen, D. Zhou, H. Wu, K. Apelt, Y. van der Weegen, K. Yang, M. Dijk, L. Daxinger, J. A. Marteijn, A. C. O. Vertegaal, M. Ljungman, , M. S. Luijsterburg

This study identifies a PAF1C-dependent pathway that restores transcription elongation after DNA damage repair in human cells.

bioRxiv · Jan 4, 2020Cell Biology