Author

P. Miesen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:Arabidopsis· 3 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

R. P. van Rij· 5 shared F. S. Varghese· 2 shared G. J. Overheul· 2 shared A. B. Crist· 1 shared A. Baidaliuk· 1 shared A. Fontaine· 1 shared A. Mattia· 1 shared A. van Laarhoven· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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5 shared papersMicrobiology

R. P. van Rij

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Author profile →

5 papers

Recent·Most cited

The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells

J. Qu, M. Schinkel, L. Chiggiato, S. Rosendo Machado, G. J. Overheul, P. Miesen, R. P. van Rij

The paper identifies the Hsf1-sHsp cascade as a pan-antiviral mechanism in mosquito cells, effective against multiple arboviruses.

bioRxiv · Feb 21, 2023Microbiology

Berberine and obatoclax inhibit SARS-CoV-2 replication in primary human nasal epithelial cells in vitro

F. S. Varghese, E. van Woudenbergh, G. J. Overheul, M. J. Eleveld, L. Kurver, N. van Heerbeek, A. van Laarhoven, P. Miesen, G. den Hartog, M. I. de Jonge, R. P. van Rij

bioRxiv · Dec 23, 2020Microbiology

Immunity to infections in arboviral vectors by integrated viral sequences: an evolutionary perspective

C. Crava, F. S. Varghese, E. Pischedda, R. Halbach, U. Palatini, M. Marconcini, A. Mattia, S. N. Redmond, Y. Afrane, D. Ayala, C. Paupy, R. Carballar-Lejarazu, P. Miesen, R. P. van Rij, M. Bonizzoni

The paper shows that nonretroviral endogenous viral elements (nrEVEs) in Aedes aegypti confer antiviral immunity by producing piRNAs, supporting their role as heritable immunity effectors.

bioRxiv · Apr 2, 2020 · PreprintEvolutionary Biology

Non-retroviral endogenous viral element limits cognate virus replication in Aedes aegypti ovaries

Y. Suzuki, A. Baidaliuk, P. Miesen, L. Frangeul, A. B. Crist, S. H. Merkling, A. Fontaine, S. Lequime, I. Moltini-Conclois, H. Blanc, R. P. van Rij, L. Lambrechts, M.-C. Saleh

The paper shows that a non-retroviral EVE in Aedes aegypti limits replication of its cognate virus, CFAV, through piRNA-mediated antiviral activity in ovaries.

bioRxiv · Mar 28, 2020Microbiology

The Tudor protein Veneno assembles the ping-pong amplification complex that produces viral piRNAs in Aedes mosquitoes

J. Joosten, P. Miesen, B. Pennings, P. W. T. C. Jansen, M. A. Huynen, M. Vermeulen, R. P. Van Rij

The paper identifies Veneno, a Tudor protein in Aedes aegypti, as essential for viral piRNA production via its role in assembling the ping-pong amplification complex with Ago3 and Piwi5.

bioRxiv · Aug 15, 2018Microbiology