Author

G. K. Bonney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:chicken / avian· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Aiderus· 1 shared A. F. Vallejo· 1 shared A. Hariharan· 1 shared A. Tijore· 1 shared A. W.-C. Koh· 1 shared A. Y.-F. Chung· 1 shared B. K. P. Goh· 1 shared B. Vilaysane· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Aiderus

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MMPs and NETs are detrimental in human CNS-tuberculosis and MMP inhibition in a mouse model improves survival

X. Y. Poh, F. K. Loh, C. Bai, H. T. Chong, W. K. Teo, J. M. Hong, Q. H. Miow, P. M. Thong, B. Vilaysane, T. H. Hu, S. Chhabra, Y. Wang, S. C. Tiong, S. M. Fong, M. Kamihigashi, , C. W. M. Ong

The paper identifies elevated MMPs and NETs in CNS-TB patients and shows MMP inhibition improves survival in a mouse model.

bioRxiv · Oct 5, 2023 · PreprintPathology

Multi-region spatial transcriptome analysis reveals cellular networks and pathways associated with hepatocellular carcinoma recurrence

A. Aiderus, P. V. Seshachalam, K. Idzham, M. Caldez, R. Shanmugam, I. N. Sari, D. H. H. Ying, S. L. Chong, K. Sekar, S. C. Chew, G. B. Chen, A. Y.-F. Chung, P. C. Cheow, J. H. Kam, A. W.-C. Koh, , P. K. H. Chow

This study uses spatial transcriptomics to analyze HCC tumor sectors and identifies endothelial cell enrichment and ligand-receptor interactions linked to disease recurrence.

bioRxiv · Jul 26, 2023 · PreprintCancer Biology

Ultrasound-mediated mechanical forces selectively kill tumor cells

A. Tijore, F. Margadant, M. Yao, A. Hariharan, C. A. Z. Chew, S. Powell, G. K. Bonney, M. Sheetz

This paper shows low-frequency ultrasound selectively kills tumor cells via a calpain-dependent mitochondrial pathway involving Piezo1 channels, with minimal damage to normal cells in animal models and patient-derived organoids.

bioRxiv · Oct 9, 2020 · PreprintCancer Biology