Author

G. L. Barry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 2 Pathology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 8 Approach:experimental assay· 7 Organism:non-human primate· 3 Organism:rat· 3 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

T. C. Friedrich· 8 shared A. M. Weiler· 6 shared S. L. O'Connor· 5 shared C. M. Newman· 4 shared D. H. O'Connor· 4 shared D. M. Dudley· 4 shared E. L. Mohr· 4 shared L. M. Stewart· 4 shared

Activity by Year

2017-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

8 shared papersMicrobiology

T. C. Friedrich

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Avian H7N9 influenza viruses are evolutionarily constrained by stochastic processes during replication and transmission in mammals

K. M. Braun, L. A. Haddock, C. M. Crooks, G. L. Barry, J. Lalli, G. Neumann, T. Watanabe, M. Imai, S. Yamayoshi, M. Ito, Y. Kawaoka, T. C. Friedrich

This study shows that H7N9 avian influenza viruses face strong evolutionary constraints during mammalian transmission, making human adaptation unlikely without rare, stochastic events.

bioRxiv · Apr 12, 2022Microbiology

Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks

K. A. Amato, L. A. Haddock, K. M. Braun, V. Meliopoulos, B. Livingston, R. Honce, G. A. Schaack, E. Boehm, C. A. Higgins, G. L. Barry, K. Koelle, S. Schultz-Cherry, T. C. Friedrich, A. Mehle

This study tracks influenza A virus diversity in ferrets, showing compartmentalized replication and stochastic bottlenecks shaping genetic diversity within lung lobes.

bioRxiv · Sep 28, 2021Microbiology

Extensive CD8β depletion does not prevent control of viral replication or protection from challenge in macaques chronically infected with a live attenuated simian immunodeficiency virus

M. S. Sutton, A. Ellis-Connell, A. J. Balgeman, G. L. Barry, A. M. Weiler, S. J. Hetzel, Y. Zhou, A. Kilby, R. Mason, K. K. Biris, J. R. Mascola, N. Sullivan, M. Roederer, T. C. Friedrich, S. L. O'Connor

This study shows that CD8β+ T cell depletion in SIV-infected macaques does not prevent viral control or protection from challenge, suggesting CD8β+ T cells are not essential for these outcomes.

bioRxiv · Apr 13, 2019Immunology

Acute-phase CD4+ T cell responses targeting invariant viral regions are associated with control of live-attenuated simian immunodeficiency virus

M. S. Sutton, A. Ellis-Connell, R. V. Moriarty, A. J. Balgeman, D. Gellerup, G. L. Barry, A. M. Weiler, T. C. Friedrich, S. L. O'Connor

This study shows that CD4+ T cell responses targeting invariant viral regions in MCMs without protective MHC alleles correlate with lower viral load during SIV infection.

bioRxiv · May 13, 2018Immunology

Molecularly barcoded Zika virus libraries to probe in vivo evolutionary dynamics

M. T. Aliota, D. M. Dudley, C. M. Newman, J. Weger-Lucarelli, L. M. Stewart, M. R. Koenig, M. E. Breitbach, A. M. Weiler, M. R. Semler, G. L. Barry, K. R. Zarbock, M. S. Mohns, E. L. Mohr, V. Venturi, N. Schultz-Darken, , D. H. O'Connor

This paper uses molecularly barcoded Zika virus to study in vivo infection dynamics in pregnant and non-pregnant macaques and mosquitoes, finding stable lineage proportions during acute infection but a rapid decline in complexity post-infection in pregnant animals.

bioRxiv · Nov 17, 2017Microbiology

Ocular and uteroplacental pathology in macaque congenital Zika virus infection

E. L. Mohr, L. N. Block, C. M. Newman, L. M. Stewart, M. Koenig, M. Semler, M. E. Breitbach, L. B. C. Teixeira, X. Zeng, A. M. Weiler, G. L. Barry, T. H. Thoong, G. J. Wiepz, D. M. Dudley, H. A. Simmons, , T. G. Golos

This study reports ocular and uteroplacental pathology in rhesus macaques infected with ZIKV during pregnancy, showing prolonged viral replication and severe fetal outcomes.

bioRxiv · Sep 30, 2017Pathology

Highly Efficient Maternal-Fetal Zika Virus Transmission in Pregnant Rhesus Macaques

S. M. Nguyen, K. M. Antony, D. M. Dudley, S. Kohn, H. Simmons, B. Wolfe, M. S. Salamat, L. B. Teixeira, G. J. Wiepz, T. H. Thoong, M. T. Aliota, A. M. Weiler, G. L. Barry, K. L. Weisgrau, L. J. Vosler, , T. G. Golos

This study infects pregnant rhesus macaques with ZIKV and observes prolonged maternal viremia and fetal tissue infection, indicating efficient vertical transmission.

bioRxiv · May 11, 2017Pathology

Oropharyngeal mucosal transmission of Zika virus in rhesus macaques

C. M. Newman, D. M. Dudley, M. T. Aliota, A. M. Weiler, G. L. Barry, M. S. Mohns, M. E. Breitbach, L. M. Stewart, C. R. Buechler, M. E. Graham, J. Post, N. Schultz-Darken, E. Peterson, W. Newton, E. L. Mohr, , T. C. Friedrich

This study assesses the risk of Zika virus transmission through mucosal contact in rhesus macaques, finding that oral secretions from infected individuals pose a low transmission risk.

bioRxiv · Feb 8, 2017Microbiology