Author

G. M. Wynne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. J. Russell· 3 shared D. B. Sattelle· 3 shared F. A. Partridge· 3 shared K. J. Else· 3 shared N. J. Willis· 3 shared R. Forman· 3 shared A. E. Brown· 2 shared A. Russell· 2 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersPharmacology & Toxicology

A. J. Russell

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 3, 2021

A novel tubulin binding molecule drives differentiation of acute myeloid leukaemia cells

T. R. Jackson, A. Vuorinen, L. Josa-Cullere…·T. Milne

The paper identifies a novel tubulin-binding molecule that induces differentiation in AML cells, reducing tumour burden and improving survival in vivo.

DOI 10.1101/2021.06.03.446952

humanbulk RNA-seq

Pharmacology & ToxicologyACS Infectious DiseasesPeer-reviewedApr 2, 2021

Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi, Heligmosomoides polygyrus and Schistosoma mansoni

F. A. Partridge, C. J. Bataille, R. Forman…·D. B. Sattelle

The paper investigates the structure-activity relationship of dihydrobenzoxazepinone (DHB) compounds against various parasitic nematodes and trematodes, identifying key structural features for anthelmintic activity.

DOI 10.1021/acsinfecdis.1c00025

mousehuman

Cancer BiologybioRxivPreprintDec 18, 2020

A phenotypic screen identifies a compound series that induces differentiation of acute myeloid leukemia cells in vitro and shows anti-tumour effects in vivo

L. Jose-Cullere, K. S. Madden, T. J. Cogswell…·A. Russell

DOI 10.1101/2020.12.18.423389

mouseexperimental assay

Pharmacology & ToxicologybioRxivApr 26, 2018

2,4-Diaminothienopyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm

F. A. Partridge, R. Forman, N. J. Willis…·D. B. Sattelle

This paper identifies a new class of anthelmintic compounds, DATPs, effective against whipworm adult and egg stages, suggesting potential for environmental control strategies.

DOI 10.1371/journal.pntd.0006487

mouseexperimental assay

Pharmacology & ToxicologybioRxivSep 11, 2017

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes

F. A. Partridge, A. E. Brown, S. D. Buckingham…·D. B. Sattelle

The paper develops an automated system for screening chemical libraries against nematodes, identifying known and novel anthelmintic compounds.

DOI 10.1016/j.ijpddr.2017.11.004

C. elegansmouse