Author

N. J. Willis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Organism:C. elegans· 1 Organism:human· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

A. J. Russell· 3 shared D. B. Sattelle· 3 shared F. A. Partridge· 3 shared G. M. Wynne· 3 shared K. J. Else· 3 shared R. Forman· 3 shared A. E. Brown· 2 shared C. J. Bataille· 2 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersPharmacology & Toxicology

A. J. Russell

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Author profile →

3 papers

Recent·Most cited

Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi, Heligmosomoides polygyrus and Schistosoma mansoni

F. A. Partridge, C. J. Bataille, R. Forman, A. E. Marriott, J. Forde-Thomas, C. Häberli, R. L. Dinsdale, J. D. O'Sullivan, N. J. Willis, G. M. Wynne, H. Whiteland, J. Archer, A. Steven, J. D. Turner, J. Keiser, , D. B. Sattelle

The paper investigates the structure-activity relationship of dihydrobenzoxazepinone (DHB) compounds against various parasitic nematodes and trematodes, identifying key structural features for anthelmintic activity.

ACS Infectious Diseases · Apr 2, 2021Peer-reviewedPharmacology & Toxicology

2,4-Diaminothienopyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm

F. A. Partridge, R. Forman, N. J. Willis, C. J. Bataille, E. A. Murphy, A. E. Brown, N. Heyer-Chauhan, B. Marinic, D. J. Sowood, G. M. Wynne, K. J. Else, A. J. Russell, D. B. Sattelle

This paper identifies a new class of anthelmintic compounds, DATPs, effective against whipworm adult and egg stages, suggesting potential for environmental control strategies.

bioRxiv · Apr 26, 2018Pharmacology & Toxicology

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes

F. A. Partridge, A. E. Brown, S. D. Buckingham, N. J. Willis, G. M. Wynne, R. Forman, K. J. Else, A. A. Morrison, J. B. Matthews, A. J. Russell, D. A. Lomas, D. B. Sattelle

The paper develops an automated system for screening chemical libraries against nematodes, identifying known and novel anthelmintic compounds.

bioRxiv · Sep 11, 2017Pharmacology & Toxicology